4.8 Article

Neutral Flavins: Green and Robust Organocatalysts for Aerobic Hydrogenation of Olefins

Journal

ORGANIC LETTERS
Volume 12, Issue 1, Pages 32-35

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol902393p

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology, Japan

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Various olefins can be hydrogenated quantitatively with neutral flavin 2 catalysts in the presence of 1-2 equiv of hydrazine under 1 atm of O(2), Vitamin B(2) derivative 2g acts as a highly efficient and robust catalyst for the present environmentally benign process producing water and nitrogen gas as the only waste products.

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