Journal
ORGANIC LETTERS
Volume 12, Issue 3, Pages 572-575Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol902764k
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Funding
- NIGMS [P50-GM067041]
- Merck
- NMR [CHE-0619339]
- MS [CHE-0443618]
- NSF
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The Lewis acid-catalyzed, three-component reaction of isatin and two 1,3-dicarbonyl compounds is reported. Reactions proceed with high efficiency under mild reaction conditions and with good functional group tolerance to afford spirooxindole pyranochromenedione derivatives.
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