Journal
ORGANIC LETTERS
Volume 12, Issue 15, Pages 3380-3383Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol101200z
Keywords
-
Categories
Funding
- Japan Science and Technology Agency (JST)
- Japan Society for the Promotion of Science (JSPS) [21350048]
Ask authors/readers for more resources
Hydrogenation of 3-quinuclidinone and bicyclo[2.2.2]octan-2-one with a combined catalyst system of RuCl(2)[(S)-binap][(R)-iphan] and t-C(4)H(9)OK in 2-propanol afforded the chiral alcohols in 97-98% ee. 2-Diphenylmethyl-3-quinuclidinone was hydrogenated with the same catalyst to the cis alcohol with perfect diastereo- and enantioselectivity. The reaction of unsymmetrical ketones with a bicyclo[2.2.1] or -[2.2.2] skeleton gave the corresponding alcohols with high stereoselectivity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
