Journal
ORGANIC LETTERS
Volume 12, Issue 4, Pages 700-703Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol9027144
Keywords
-
Categories
Funding
- U.S. Department of Energy
- Robert H. Cole Foundation
- University of Tennessee Summer Undergraduate Research
Ask authors/readers for more resources
Tetrabutylammonium tribromide (TBATB) has been found to be a unique bromodeboronation reagent for organotrifluoroborates. When compared to previously reported bromodeboronation methods, the mild and metal-free reaction conditions tolerate a wider range of functional groups. High regio- and chemoselectivity are observed in the presence of both unsaturated carbon-carbon bonds and aldehyde functional groups. An efficient synthetic route to (Z)-dibromoalkenes from terminal alkynes has been developed using the TBATB-mediated bromodeboronation as a key step.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available