4.8 Article

Reaction of α-Ene-Vinylcyclopropanes: Type II Intramolecular [5+2] Cycloaddition or [3+2] Cycloaddition?

Journal

ORGANIC LETTERS
Volume 12, Issue 6, Pages 1332-1335

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol100237h

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Funding

  1. Natural Science Foundation of China [20825205, 20772007, 20672005]
  2. National Basic Research Program of China-973 Program [2010CB833203]

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Exposure of alpha-ene-VCPs to catalytic [Rh(dppm)]SbF6 led to the discovery of a novel Rh(I)-catalyzed [3+2] reaction, which was shown to be efficient for the construction of 5/6- and 5/7-bicyclic compounds rather than the anticipated type II [5+2] products.

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