4.8 Article

Titanocene-Catalyzed Conjugate Reduction of alpha,beta-Unsaturated Carbonyl Derivatives

Journal

ORGANIC LETTERS
Volume 12, Issue 1, Pages 44-47

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol9024315

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Funding

  1. University of Notre Dame

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A titanocene-catalyzed conjugate reduction of alpha,beta-unsaturated carbonyl derivatives has been developed. A series of carbonyl compounds including aldehydes, ketones, esters, and amides proved viable In the reduction process providing an efficient, chemoselective method for the catalytic reduction of unsaturated carbonyl derivatives.

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