Journal
ORGANIC LETTERS
Volume 12, Issue 10, Pages 2306-2309Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol100666v
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Funding
- National Institutes of Health [GM 48498]
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A versatile method for the synthesis of 3,3-diaryloxindoies via Pd-catalyzed alpha-arylations or an SNAr reaction is described. The reaction proceeds using mild base, is tolerant of a variety of functional groups, and is capable of preparing hindered all-carbon quaternary centers.
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