Journal
ORGANIC LETTERS
Volume 12, Issue 13, Pages 2966-2969Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol1009812
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Diarylprolinol was found to be an effective organocatalyst of the direct, enantioselective aldol reaction of commercially available polymeric ethyl glyoxylate, affording gamma-ethoxycarbonyl-beta-hydroxy aldehydes, versatile synthetic intermediates, in good yield with excellent enantioselectivity.
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