4.8 Article

Termitomycamides A to E, Fatty Acid Amides Isolated from the Mushroom Termitomyces titanicus, Suppress Endoplasmic Reticulum Stress

Journal

ORGANIC LETTERS
Volume 12, Issue 21, Pages 5012-5015

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol102186p

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology of Japan [17035037]
  2. Grants-in-Aid for Scientific Research [17035037] Funding Source: KAKEN

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Five fatty acid amides, termitomycamides A to E (1 to 5), were isolated from the giant edible mushroom Termitomyces titanicus. The structures of 1-5 were determined by the interpretation of spectral data and/or synthesis. Compounds 2 and 5 showed protective activity against endoplasmic reticulum stress-dependent cell death.

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