Journal
ORGANIC LETTERS
Volume 12, Issue 20, Pages 4524-4527Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol101831b
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Funding
- National Science Foundation
- Novartis Pharma AG
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Diels-alder reactions of cyclic isoimidium salts are described. The corresponding cycloadducts are obtained with high regio- and stereoselectivity The use of homochiral cyclic isoimidium salts delivers cycloadducts with excellent diastereoselectivity (>99.1) that can be efficiently converted to enantiometrically pure lactones
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