4.8 Article

Synthesis of the Indolizino[7,6-c]quinoline Alkaloid Isaindigotidione

Journal

ORGANIC LETTERS
Volume 12, Issue 20, Pages 4628-4631

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol101890t

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Funding

  1. Harvard NeuroDiscovery Center

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The first synthesis of isaindigotidione has been developed utilizing a reaction sequence including an asymmetric rhodium-catalyzed 1,4-conjugate addition, an intramolecular aldol reaction, and a lactamization

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