4.8 Article

Nickel-Catalyzed [2+2+2] Cycloaddition of Two Enones and an Alkyne

Journal

ORGANIC LETTERS
Volume 12, Issue 15, Pages 3450-3452

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol101264r

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Funding

  1. MEXT [21245028, 21750102]
  2. Nagase Science and Technology Foundation
  3. Japan Petroleum Institute
  4. Grants-in-Aid for Scientific Research [21750102] Funding Source: KAKEN

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A fully intermolecular [2 + 2 + 2] cycloaddition of two enones and an alkyne has been achieved. This reaction proceeds stereoselectively to give one diastereomer as a sole product.

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