4.8 Article

Intramolecular Imino Diels-Alder Approach to the Synthesis of the Aspidosperma Alkaloid from 3,5-Dibromo-2-pyrone

Journal

ORGANIC LETTERS
Volume 12, Issue 9, Pages 2012-2014

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol100489z

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Funding

  1. National Research Foundation [KRF-2008-313-C00467, 2009-0080752]
  2. National Research Foundation of Korea [2008-313-C00467, 2009-0080752] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A new synthetic route to the key framework of aspidosperma alkaloid was devised from the cycloadduct of 3-(2-nitrophenyl)-5-bromo-2-pyrone via intramolecular imino Diels-Alder reaction.

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