4.8 Article

Tandem Ir-Catalyzed Allylic Substitution Reaction of Allyl Sulfinates and Isomerization

Journal

ORGANIC LETTERS
Volume 12, Issue 4, Pages 800-803

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol902873q

Keywords

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Funding

  1. NSFC [20872159, 20821002, 20932008]
  2. National Basic Research Program of China [2009CB825300]

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An efficient method for the synthesis of trisubstituted vinyl sulfones is reported. Using the [Ir(COD)Cl](2)/phosphoramidite ligand (L-1)/DBU, trisubstituted vinyl sulfones could be synthesized from allyl sulfinates in high yields as exclusively E isomers.

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