Journal
ORGANIC LETTERS
Volume 12, Issue 4, Pages 860-863Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol902913j
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Funding
- DGICYT (Spain) [CTQ2009-07758]
- Grupo Ferrer (Barcelona)
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Unsaturated lactams with endo- or exocyclic C-C double bonds constitute a set of reactive inputs that serve as the electron-rich olefin component in Povarov reactions. These substrates afford the multicomponent adducts in convenient yields and offer a wide range of structural diversity. Postcondensation transformations allow direct access to a variety of lactam-fused and amide-substituted quinoline derivatives.
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