Journal
ORGANIC LETTERS
Volume 12, Issue 2, Pages 376-379Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol902451h
Keywords
-
Categories
Funding
- NSERC
- Inorganic Chemistry Exchange (ICE)
Ask authors/readers for more resources
B(C6F5)(3)-catalyzed bis(hydrosilylation) of alpha-diketones can give high diastereomeric excess of either meso/anti (small silanes and disilane reagents) or dl/syn (bulky silanes) silyl-protected 1,2-diols. This easily tuned diastereoselectivity is rationalized based on the classic Felkin-Anh model applied to a mechanism relying on Si-H abstraction by the electrophilic borane reagent.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available