Journal
ORGANIC LETTERS
Volume 12, Issue 10, Pages 2318-2321Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol1006289
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Funding
- NSF [CHE-0907905]
- NIH [5 F32 GM085930]
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Two new cell-trappable fluorescent probes for nitric oxide (NO) are reported based on either incorporation of hydrolyzable esters or conjugation to aminodextran polymers. Both probes are highly selective for NO over other reactive oxygen and nitrogen species (RONS). The efficacy of these probes for the fluorescence imaging of nitric oxide produced endogenously in Raw 264.7 cells is demonstrated.
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