4.8 Article

Copper-Catalyzed Intramolecular N-Arylation of Quinazolinones: Facile Convergent Approach to (-)-Circumdatins H and J

Journal

ORGANIC LETTERS
Volume 12, Issue 16, Pages 3716-3719

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol101597p

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Funding

  1. CSIR, New Delhi
  2. Department of Science and Technology, New Delhi

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A copper-catalyzed intramolecular N-arylation of a quinazolinone nucleus that furnished the central benzodiazepine core unit has been demonstrated to accomplish an efficient convergent total synthesis of (-)-circumdatins H and J.

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