Journal
ORGANIC LETTERS
Volume 12, Issue 18, Pages 4094-4097Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol101681r
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Funding
- EPSRC
- Engineering and Physical Sciences Research Council [EP/F029772/1] Funding Source: researchfish
- EPSRC [EP/F029772/1] Funding Source: UKRI
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Olefin cross-metathesis (CM) provides a short and convenient entry to diverse trans-gamma-aminoenones. When exposed to either acid or Heck arylation conditions, these intermediates are converted to mono-, di-, or trisubstituted pyrroles. The value of this chemistry is demonstrated by its application to the tetrasubstituted pyrrole subunit of Atorvastatin.
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