Journal
ORGANIC LETTERS
Volume 12, Issue 19, Pages 4288-4291Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol101698a
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- Bundesministerium fur Bildung und Forschung [03X4612J]
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Multiply fluorine-substituted iodo anisoles are efficiently coupled in an Ullmann-type reaction to provide the corresponding bisanisoles. The coupling is selective and even tolerates bromo moieties. Subsequent deprotection of hydroxy groups gives access to highly fluorinated biphenols.
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