Journal
ORGANIC LETTERS
Volume 12, Issue 12, Pages 2758-2761Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol1008685
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Funding
- Danish National Research Foundation
- H. Lundbeck A/S
- OChem graduate school
- Aarhus University
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A Au(I)-catalyzed hydroamination or hydration of 1,3-diynes to access 2,5-diamidopyrroles and 2,5-diamidofurans has been developed. This method can also be expanded to 2,5-disubstituted furans and 1,2,5-trisubstituted pyrroles including the formation of deuterated heterocycles and O-18-labeled furans.
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