Journal
ORGANIC LETTERS
Volume 12, Issue 10, Pages 2210-2213Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol100424y
Keywords
-
Categories
Funding
- Swedish Research Council
- Chemical biology platform at the University of Gothenburg
Ask authors/readers for more resources
A novel combination of SmI2, KHMDS, and TsCN can be utilized to introduce a cyano group into structurally diverse and highly sensitive 2-alkyl-chroman-4-ones. Subsequent oxidation allows the formed 2-alkyl-3-cyanochromones to be isolated in yields ranging from 49 to 77%. In addition, alpha-bromoketones and esters were found to undergo equally effective alpha-cyanation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available