Journal
ORGANIC LETTERS
Volume 11, Issue 2, Pages 265-268Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol802336m
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- CONACyT [166350]
- DGAPA [IN209206]
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The application of air stable preformed [(R)-BINAP]PdBr2, [(S)-BINAP]PdBr2, [(R)-Tol-BINAP]PdBr2, and [(S,S)-CHIRAPHOS]PdBr2 complexes in the one-pot asymmetric reductive amination of various carbonyl compounds, leading to chiral amines in very good yields with high enantioselectivities (<99% ee), is reported.
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