4.8 Article

PPh3-Catalyzed Domino Reaction: A Facile Method for the Synthesis of Chroman Derivatives

Journal

ORGANIC LETTERS
Volume 11, Issue 4, Pages 991-994

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol802917d

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Funding

  1. National Natural Science Foundation of China [20772061]
  2. Natural Science Foundation of Tianjin [05YFJMJC00600]

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A novel domino reaction catalyzed by triphenylphosphine was developed for synthesis of the highly functionalized chroman derivatives. The first example that the gamma-CH3 of allenoate undergoes cyclization to form chroman derivates was reported.

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