4.8 Article

Brucine-Derived Amino Alcohol Catalyzed Asymmetric Henry Reaction: An Orthogonal Enantioselectivity Approach

Journal

ORGANIC LETTERS
Volume 11, Issue 24, Pages 5682-5685

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol902380z

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Funding

  1. IUPUI
  2. NSF-MRI [CHE-0619254]

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A new approach to both enantioenriched Henry products is developed by use of different molecularities of metal-ligand complexes generated from Cu(I) and Zn(II) metals with readily available chiral amino alcohol 1.

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