Journal
ORGANIC LETTERS
Volume 11, Issue 6, Pages 1357-1360Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol900150u
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Funding
- NSERC
- University of Ottawa
- Sloan Foundation
- Research Corporation
- Merck-Frosst
- Amgen
- Eli Lilly
- Astra Zeneca
- Boehringer Ingelheim
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Subjection of N-methyl 6- and 7-azaindole N-oxides to a Pd(OAc)(2)/DavePhos catalyst system enables regioselective direct arylation of the azine ring. Following deoxygenation, 7-azaindole substrates undergo an additional regioselective azole direct arylation event in good yield.
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