4.8 Article

Multiresponsive Switchable Diarylethene and Its Application in Bioimaging

Journal

ORGANIC LETTERS
Volume 11, Issue 17, Pages 3818-3821

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol9014267

Keywords

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Funding

  1. National Science Foundation of China [20771027, 30890141]
  2. National Basic Research Program of China [2009CB930400]
  3. Specialized Research Fund for the Doctoral Program of Higher Education [200802460007]
  4. Shanghai Sci. Tech. Comm. [08JC1402400]
  5. Shanghai Leading Academic Discipline Project [B108]

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A multiresponsive fluorescent switch based on diarylethene and terpyridine units was developed. It exhibits effective switchable fluorescence which can be controlled by UV/visible light or metal Ion/EDTA In solution. More importantly, having low toxicity, It can enter live cells as a fluorescent probe and can also serve as a detector for the biological process of metal ion transmembrane transport.

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