Journal
ORGANIC LETTERS
Volume 11, Issue 11, Pages 2377-2379Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol900235s
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- Zymes
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The trick to carrying out regiocontrolled aminations of allylic alcohols in water as the only medium is use of a nanomicelle's interior as the organic reaction solvent. When HCO2Me is present, along with the proper base and source of catalytic Pd, allylic amines are cleanly formed at room temperature.
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