Journal
ORGANIC LETTERS
Volume 11, Issue 11, Pages 2301-2304Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol900636w
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- Ministerio de Ciencia e Innovacion [CTQ2007-61704/BQU]
- Generalitat de Catalunya
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Three new bis(cyclobutane) beta-dipeptides have been synthesized from appropriate derivatives of cis- and trans-2-aminocyclobutane-1-carboxylic acid, respectively. The predominance of eight-membered hydrogen-bonded rings has been manifested for (trans,trans)- and (trans,cis)-beta-dipeptides while the formation of six-membered rings is preferred for the (cis,trans)- beta-dipeptide similarly to the previously described (cis,cis)-diastereomer.
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