Journal
ORGANIC LETTERS
Volume 11, Issue 2, Pages 453-456Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol802529p
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Funding
- New Century Excellent Talents in University [NCET-06-0711]
- National Natural Science Foundation of China [20572020, 20872112]
- Zhejiang Provincial Natural Science Foundation of China [Y407116]
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A novel protocol for the 1,2-addition reactions of electron-deficient aryl aldehydes with arylboronic acids using an inexpensive and environmentally benign iron catalyst is reported. In the presence of FeCl3 and 2-(di-tert-butylphosphino)biphenyl, 1,2-addition reactions of various electron-deficient aryl aldehydes with arylboronic acids provided the corresponding biaryl methanols in moderate to excellent yields.
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