4.8 Article

Carbon-Carbon Formation via Ni-Catalyzed Suzuki-Miyaura Coupling through C-CN Bond Cleavage of Aryl Nitrile

Journal

ORGANIC LETTERS
Volume 11, Issue 15, Pages 3374-3377

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol901217m

Keywords

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Funding

  1. NSFC [20672006, 20821062]
  2. MOST of China [2009CB825300]

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The Suzuki-Miyaura coupling of aryl nitriles with aryl/alkenyl boronic esters is reported. With this method, the cyano group could be applied as a protecting group of arenes and finally as a leaving group to further construct polyaryl scaffolds.

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