4.8 Article

Metal-Ion-Induced Folding and Dimerization of a Glycoluril Decamer in Water

Journal

ORGANIC LETTERS
Volume 11, Issue 17, Pages 3918-3921

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol901539q

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Funding

  1. National Science Foundation [CHE-0615049, CHE-0914745]
  2. University of Maryland

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In a process reminiscent of RNA folding, acyclic glycoluril decamer (+/-)-1 undergoes double helical assembly (red/green strands) in water triggered by the neutralization of regions of high electrostatic surface potential by metal cations (Li+, Na+, K+, Ca2+).

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