4.8 Article

Carbolithiation of Conjugated Enynes with Aryllithiums in Microflow System and Applications to Synthesis of Allenylsilanes

Journal

ORGANIC LETTERS
Volume 11, Issue 16, Pages 3614-3617

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol901352t

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Funding

  1. NEDO

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Carbolithlation of conjugated enynes with aryllithiums generated by Br-Li exchange reaction followed by reaction of the allenyllithium compounds with chlorosilanes was carried out in a microflow system to obtain various allenylsilanes in good yields.

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