Journal
ORGANIC LETTERS
Volume 11, Issue 14, Pages 2992-2995Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol900949y
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Funding
- CNRS
- Universite Montpellier II
- European Network of Excellence Magmanet [NMP3-CT-2005-515767]
- UFI [GF/IR/732/07, 25]
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Water-soluble biocompatible rhamnose-coated Fe3O4 nanoparticles of 4.0 nm are obtained by covalent anchorage of rhamnose on the nanoparticles surface via a phosphate linker. These nanoparticles present superparamagnetic behavior and nuclear relaxivities in the same order of magnitude as Endorem that make them potential magnetic resonance imaging (MRI) contrast agents of a second generation, where the saccharides represent also specific ligands able to target lectins on skin cells.
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