Journal
ORGANIC LETTERS
Volume 11, Issue 9, Pages 1991-1993Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol900444h
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- Loughborough University
- University of East Anglia
- Charnwood Molecular Ltd
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Concise highly enantioselective three-step syntheses are described for (-)-(3'S)-lomatin and (+)-(3'S,4'R)-trans-khellactone from 7-hydroxycoumarin in 97% ee and in 57% and 58% overall yields, respectively, using nonaqueous enantioselective epoxidation by an iminium salt as the key step.
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