Journal
ORGANIC LETTERS
Volume 11, Issue 13, Pages 2912-2915Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol900779v
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- GlaxoSmithKline
- CNRS
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Hydrazinocyclohexadienes, easily prepared by an ene-reaction between commercially available azodicarboxylate reagents and cyclohexadiene, are interesting substrates for desymmetrization reactions. Under Sharpless asymmetric dihydroxylation conditions, they can lead efficiently to several chiral building blocks as well as advanced precursors of biologically active compounds.
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