Journal
ORGANIC LETTERS
Volume 11, Issue 14, Pages 2996-2999Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol900972j
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Funding
- NSERC
- Canadian Cancer Society
- Michael Smith Foundation for Health Research
- UBC University
- Canada Research Chair
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Laboratory cultures of the fungus Plectosphaerella cucumerina obtained from marine sediments collected in Barkley Sound, British Columbia, yielded the novel alkaloids plectosphaeroic acids A (1) to C (3). The alkaloids 1-3 are inhibitors of indoleamine 2,3-dioxygenase (IDO).
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