Journal
ORGANIC LETTERS
Volume 11, Issue 2, Pages 405-408Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol802700w
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Funding
- Ministry of Education [R143-000-280-112]
- Agency for Science, Technology, and Research (A*Star) of Singapore [R154-000-274-305]
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We have synthesized Singapore Green (SG), a structural hybrid of Tokyo Green and Rhodamine 110. This new dye is a green light-emitting substitute for 7-aminocoumarin, a blue fluorescent dye widely used in enzymatic assays. SG-conjugated peptide substrates were successfully synthesized and used in microarray-based protease substrate profiling and live-cell imaging experiments.
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