Journal
ORGANIC LETTERS
Volume 11, Issue 21, Pages 5082-5084Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol902110a
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- Chugai Pharmaceutical Co
- Caltech/City of Hope Medical Research Fund
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An efficient synthesis of the C(7)-C(23) fragment 2 of iriomoteolide-1a (1) has been accomplished via a B-alkyl Suzuki-Miyaura cross-coupling reaction followed by deprotection and cyclization to form the cyclic hemiketal core.
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