Journal
ORGANIC LETTERS
Volume 11, Issue 6, Pages 1209-1212Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol8027362
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Funding
- Nanyang Technological University
- Singapore Ministry of Education Academic Research Fund Tier 2 [T206B1221, T207B1220RS]
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An efficient method for the Barbier-type alkylation reaction of various nitrones (including chiral version) and alkyl halides in water is described. The amines and hydroxylamines can be obtained in good yields, depending on the judicious choice of the metal complexes used.
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