Journal
ORGANIC LETTERS
Volume 11, Issue 11, Pages 2469-2472Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol900847t
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Funding
- National Natural Science Foundation of China [20672065, 20732004]
- Chinese 863 Project [2007AA02Z160, 2006DFA43030]
- Programs for New Century Excellent Talents in University [NCET-05-0062]
- Changjiang Scholars and Innovative Research Team in University (PCSIRT) in China [IRT0404]
- Beijing Department of Education [XK100030514]
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A simple and efficient copper-catalyzed method for synthesis of 3,4-disubstituted isoquinolin-1(2H)-one derivatives via cascade reactions of substituted 2-halobenzamides with beta-keto esters under mild conditions has been developed, and the method has economical and practical advantages.
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