Journal
ORGANIC LETTERS
Volume 10, Issue 19, Pages 4387-4389Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801931v
Keywords
-
Categories
Funding
- Grant-in-Aid for Scientific Research
- Ministry of Education, Culture, Sports, Science and Technology, Japan
- NIH
Ask authors/readers for more resources
Chiral dienes possessing the bicyclo[2.2.2]octadiene framework were prepared readily through the [4 + 2] cycloaddition of (R)-alpha-phellandrene with methyl propiolate as the key step. Diene 9, substituted with a tertiary alcohol on one of the two double bonds, is prepared in just one step from the cycloadduct and is highly effective as a chiral ligand for rhodium-catalyzed asymmetric conjugate addition reactions, giving the corresponding addition products with higher enantioselectivity than other chiral dienes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available