4.8 Article

Assisted ruthenium-catalyzed C-H bond activation: Carboxylic acids as cocatalysts for generally applicable direct arylations in apolar solvents

Journal

ORGANIC LETTERS
Volume 10, Issue 11, Pages 2299-2302

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol800773x

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Catalytic amounts of aromatic carboxylic acid MesCO(2)H enabled efficient ruthenium-catalyzed direct arylations in apolar solvents with unparalleled broad scope via a concerted deprotonation-metalation mechanism.

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