Journal
ORGANIC LETTERS
Volume 10, Issue 20, Pages 4541-4544Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801841m
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- WSU
- WSU Research Grant [145767]
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A one-pot, two-step synthesis of the title compounds employs a multicomponent Ugi condensation reaction, microwave irradiation, and Fe(0) as a reductant. Two pathways are accessible; both routes utilize bifunctional, o-nitro-substituted arenes leading to either C2, N4, C5 substitution (A) or C2, N4 substitution (B).
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