Journal
ORGANIC LETTERS
Volume 10, Issue 13, Pages 2629-2632Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol800518j
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N-Propargylic beta-enaminones have been used as common intermediates for the synthesis of polysubstituted pyrroles and pyridines. Best results have been obtained using DMSO as solvent. In the presence of CS(2)CO(3) N-propargylic beta-enaminones are cyclized to pyrroles in good to high yields, whereas omitting bases and using CuBr leads to the selective formation of pyridines.
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