Journal
ORGANIC LETTERS
Volume 10, Issue 21, Pages 4899-4901Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801985q
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Funding
- SASOL Technology
- Natural Sciences and Engineering Research Council of Canada
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Tandem palladium-catalyzed N,C-coupling/carbonylation, under 10 atm of carbon monoxide and at 110 degrees C, is a novel and efficient method for the preparation of 2-carboxyindoles. The catalyst system tolerates a variety of functional groups, and the noted indoles were obtained in good isolated yields.
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