Journal
ORGANIC LETTERS
Volume 10, Issue 20, Pages 4513-4516Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801784a
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Funding
- State Key Program of Basic Research of China [2006BAI01B02]
- National Natural Science Foundation of China [20721003, 20872153]
- Talent Research Group from the Shanghai Science and Technology Commission
- 863 Hi-Tech Program of China [2006AA020602]
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A practical and promising protocol was developed for N-arylations of various amines with differently substituted aryl halides. The processes are efficiently promoted by the catalyst system involving the environmentally benign Fe2O3 and the universal ligand L-proline. The versatility, convenient operation, low cost, and environmental friendliness, in combination with the high yields, render this method viable for use in both laboratory research and larger industrial scales.
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