4.8 Article

One-pot synthesis of oligosaccharides by combining reductive openings of benzylidene acetals and glycosylations

Journal

ORGANIC LETTERS
Volume 10, Issue 15, Pages 3247-3250

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol801076w

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Funding

  1. NIGMS NIH HHS [R01 GM065248, R01 GM061761, R01GM065248, R01 GM065248-06] Funding Source: Medline

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Combining triflic acid-promoted glycosylations of trichloroacetimidates with reductive opening of benzylidene acetals with triflic acid and triethylsilane as one-pot procedures provides access to a wide range of disaccharides and 2,4- and 3,4-branched trisaccharides.

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