Journal
ORGANIC LETTERS
Volume 10, Issue 4, Pages 533-536Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol702718z
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Tributyltin hydride-mediated radical reactions of organic halides were successfully carried out in a continuous flow system using a microreactor. The reactions proceeded within a very short period of time, coupled with quickly decomposing radical initiators such as V-65 and V-70. The continuous flow reaction system was applied to gram scale synthesis of a key intermediate for furofuran lignans.
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