Journal
ORGANIC LETTERS
Volume 10, Issue 20, Pages 4633-4636Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801932z
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- Natural Sciences and Engineering Research Council of Canada (NSERC)
- University of Toronto
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Novel tetracyclic and pentacyclic indole derivatives can be prepared from readily available gem-dibromovinyl substrates in a single step by means of an efficient Pd-catalyzed domino Buchwald-Hartwig amination/direct arylation reaction. Enhanced reactivity and selectivity are obtained by the addition of silver salts.
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